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Treatment of female pattern hair loss with a combination of spironolactone and minoxidil
Carlijn Hoedemaker, Sylvia van Egmond and Rodney Sinclair
Department of Dermatology, St Vincent's Hospital, University of Melbourne, and Department of Medicine and Skin and Cancer Foundation, Melbourne, Victoria, Australia
Correspondence to Professor Rodney Sinclair, Department of Dermatology, St. Vincent's Hospital, PO Box 2900, Fitzroy, Vic. 3065, Australia. Email: [email protected]
Carlijn Hoedemaker, MB BS. Sylvia van Egmond, MB BS. Rodney Sinclair, FACD.
Copyright © 2007 The Authors; Journal compilation © 2007 The Australasian College of Dermatologists
Abstract
A 53-year-old woman with clinical evidence of female pattern hair loss and histological evidence of androgenetic alopecia was initially treated with the oral antiandrogen spironolactone 200 mg daily. Serial scalp photography documented hair regrowth at 12 months; however, the hair regrowth plateaued, and at 24 months there had been no further improvement in hair density. Twice daily therapy with topical minoxidil 5% solution was then introduced and further regrowth documented, confirming the additive effect of combination therapy.
Carlijn Hoedemaker, Sylvia van Egmond and Rodney Sinclair
Department of Dermatology, St Vincent's Hospital, University of Melbourne, and Department of Medicine and Skin and Cancer Foundation, Melbourne, Victoria, Australia
Correspondence to Professor Rodney Sinclair, Department of Dermatology, St. Vincent's Hospital, PO Box 2900, Fitzroy, Vic. 3065, Australia. Email: [email protected]
Carlijn Hoedemaker, MB BS. Sylvia van Egmond, MB BS. Rodney Sinclair, FACD.
Copyright © 2007 The Authors; Journal compilation © 2007 The Australasian College of Dermatologists
Abstract
A 53-year-old woman with clinical evidence of female pattern hair loss and histological evidence of androgenetic alopecia was initially treated with the oral antiandrogen spironolactone 200 mg daily. Serial scalp photography documented hair regrowth at 12 months; however, the hair regrowth plateaued, and at 24 months there had been no further improvement in hair density. Twice daily therapy with topical minoxidil 5% solution was then introduced and further regrowth documented, confirming the additive effect of combination therapy.
