Equol (4',7-isoflavandiol) is an isoflavandiol[1] metabolized from daidzein, a type of isoflavone, by bacterial flora in the intestines.[2] While endogenous estrogenic hormones such as estradiol are steroids, equol is a nonsteroidal estrogen. However, only about 30-50% of people have intestinal bacteria that make equol.[3] Equol may have beneficial effects on the incidence of prostate cancer[4] and physiological changes after menopause.[5] Other benefits may be realized in treating male pattern baldness, acne, and other problems because it functions as a DHT blocker.[6] S-Equol preferentially activates estrogen receptor type
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